产品货号：
Z14969
中文名称：
Cyclin E2/CCNE2抗体
英文名称：
Anti-Cyclin E2/CCNE2 Antibody
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Cyclin E2/CCNE2 Antibody |
| 指标别名 | CCNE2;CYCE2;cyclin E2;G1/S specific cyclin E2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB |
| 基因名称 | CCNE2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids at the carboxyl terminus of the Cyclin E2 protein. |
| 计算分子量 | 47kDa |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | This affinity purified antibody is directed against mouse Cyclin E2 protein.The product was affinity purified from monospecific antiserum by immunoaffinity chromatography.A BLAST analysis was used to suggest cross-reactivity with Cyclin E2 protein from human based on 100% homology with the immunizing sequence.Cross-reactivity with Cyclin E2 from rat is also predicted based on a 91% homology with the immunizing sequence.Reactivity against homologues from other sources is not known. |
| 浓度 | 1.17mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | This antibody is suitable for Cancer,Immunology and Nuclear Signaling research.Cyclin E was first identified by its ability to rescue growth of yeast deficient in G1 Cyclins,indicating a role in G1 or G1/S transitions.Over-expression of Cyclin E has been observed in a variety of human tumors.Multiple isoforms of Cyclin E are expressed in tumors but not in normal tissues,suggesting a post-transcriptional regulation of Cyclin E.?Cyclin E2 associates with Cdk2 in a functional kinase complex that is inhibited by both p27Kip1 and p21Cip1.The catalytic activity associated with Cyclin E2 complexes is cell cycle regulated and peaks at the G1/S transition.?Unlike Cyclin E1,which is expressed in most proliferating normal and tumor cells,Cyclin E2 levels were low to undetectable in non-transformed cells and increased significantly in tumor-derived cells. |
| Uniprot ID | Q9Z238 |
| 基因名全称 | G1/S-specific cyclin-E2 |
| 推荐稀释比 | ELISA:1:20,000 - 1:85,000 IP:1:100 WB:1:200 - 1:2,000 |
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